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ȣ - 540924 275 |
Carotid IMT is not predictive of future cerebro-cardiovascular event in relatively young patients |
가톨릭 대학교 의과대학 순환기 내과 |
최윤석, 윤호중,정우백,김지희,황희정,이재범,박철수,이만영,정욱성,승기배 |
Introduction: Carotid IMT is surrogate markers of cerebro-cardio vascular event (CCVE) in old age. We evaluated whether thickened carotid IMT in young patients predicts the future event(CCVE) by the large cohort long-term follow-up data.
Method: Among the 3920 patients (male: female=2527:1393,mean age=65±19), Long-term outcomes of relative young age(<50 years) were analyzed. Total 315 patients(mean age= 42±7 years, male=76.3%) were divided into quartile groups along the right maximal and mean carotid IMT. Mean follow up duration was 41±17months. CCVE were including the stroke, cardiac death, nonfatal myocardial infarction. We compare the incidence of CCVE between the highest and lowest quartile groups during the follow-up period.
Results: The range of right maximal and mean IMT in the four quartile groups(IQR) were showed (table 1). Kaplan-Meier Survival analysis showed that there were no significant differences in CCVE between highest and lowest IQR groups
Conclusion: Carotid IMT was not predictive of future cerebro -cardiovascular events in the relatively young patients. Clinical significance of carotid IMT in the young patients might be different from elderly patients
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Right IMT |
25 th |
50th |
75th |
maximal IMT (mm) |
0.59 |
0.90 |
1.00 |
CCVE |
0 |
1 |
8 |
mean IMT(mm) |
0.53 |
0.62 |
0.86 |
CCVE |
0 |
4 |
5 | CCVE; Cerebro-cardiovascular event
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