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ȣ - 540819 154 |
Distribution of Cardiac Disorders Causing Improvement of Left Ventricular Systolic Function |
전북대학교 의학전문대학원 내과학교실 심장내과 |
이선화, 김원호, 김선희, 박윤지, 송민주, 이상록, 이경석, 채제건, 고재기 |
Background: Various heart diseases result in LV systolic dysfunction. We invested the distribution of cardiac disorders causing improvement of LV EF.
Methods: 461 patients whose initial LV EF was ≤50% and follow-up LV EF increased ≥10% were enrolled. Heart diseases were arbitrarily divided into 7 categories in order of frequency: 1) ischemic heart disease(IHD); 2) tachycardia-induced cardiomyopathy(TCM); 3) dilated cardiomyopathy(DCM); 4) stress-induced cardiomyopathy(SCM); 5) hypertensive cardiomyopathy(HyCM); 6) valvular heart disease(VHD); and 7) other diseases.
Results: Mean age was 63.3±14.4 years. 267 patients (57.9%) were male. Mean initial LV EF was 34.0±9.0%, follow-up EF was 51.9±7.9%, and mean EF change was 17.9±7.0%. Follow-up echo was performed 11.7±11.8 (0.1~61) months after initial study. IHD and TCM were the 2 most frequent etiologies of LV EF improvement (29.1% and 24.3%) (table). Both of initial and follow-up LV EF were lowest in DCM (27.2±6.9% and 46.9±8.2%). Initial and follow-up LV EF were highest in VHD (37.4±9.0%) and SCM (55.3±6.1%), respectively.
Conclusion: IHD and TCM were the 2 most frequent categories causing improvement of LV EF accounting for more than 50%.
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IHD |
TCM |
DCM |
SCM |
HyCM |
VHD |
Other |
Number |
134 |
112 |
64 |
48 |
46 |
32 |
25 |
Age (years) |
67.2±11.7 |
66.5±12.4 |
59.4±11.4 |
68.6±11.8 |
52.9±16.9 |
58.8±14.0 |
63.3±14.4 |
Male (%) |
58.2 |
59.8 |
73.4 |
22.9 |
60.9 |
71.9 |
52.0 |
Initial LV EF (%) |
36.7±8.9 |
32.6±8.7 |
27.2±6.9 |
34.4±7.4 |
34.8±9.4 |
37.4±9.0 |
37.1±6.9 |
F/U LV EF (%) |
52.5±8.3 |
51.5±7.1 |
46.9±8.2 |
55.3±6.1 |
51.7±8.2 |
55.3±6.6 |
53.8±5.0 |
EF change (%) |
15.8±5.4 |
18.9±7.7 |
19.7±7.3 |
20.9±7.5 |
16.9±6.8 |
17.9±7.7 |
16.8±5.3 |
Echo F/U interval (m) |
15.3±12.3 |
11.6±11.7 |
12.8±9.9 |
2.0±3.3 |
11.7±11.4 |
12.1±12.0 |
9.0±14.4 |
Initial LVEDD (mm) |
53.5±8.0 |
55.6±7.1 |
64.2±8.3 |
49.7±5.2 |
57.0±8.3 |
58.4±9.8 |
52.6±9.3 |
F/U LVEDD (mm) |
51.2±6.2 |
52.4±6.6 |
56.4±6.5 |
45.6±4.8 |
52.5±8.7 |
51.4±5.4 |
50.1±7.0 |
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