Background: Myocardial milking showed characteristic early diastolic peaking in coronary doppler. But there was no study to catch this wave by transthoracic echocardiography (TTE). We assessed the characteristic waveform in myocardial milking by TTE and evaluated the effect of medication (calcium channel blocker, CCB) in coronary Doppler. Methods: A total of 15 patients (male 80.2%, mean age 59 짹 14.2) and age-matched 18 controls (male 72.1%, mean age 60 짹 23.8) with chest pain was enrolled. They were performed coronary angiography and TTE for coronary doppler. Patients in milking group was taken medication (CCB) for 1 years and TTE for coronary Doppler was followed. Results: There was significantly increased peak diastolic velocity and mean diastolic velocity in milking group (53.2 짹 22.57 vs 29.2 짹 9.22 cm/sec, p=0.001 ; 33.8 짹 20.96 vs 21.5 짹 8.00 cm/sec, p=0.049). But there was no significant change of coronary Doppler after medication (CCB, 10.2 짹 3.24 months). Conclusion: Transthoracic echocardiography can reveal the characteristic early diastolic peaking with coronary Doppler in myocardial milking, which was induced by systolic compression and early diastolic decompression of coronary artery by myocardium. Key words ; myocardial milking, coronary Doppler, echocardiography, calcium channel blocker