Background;Cypher sirolimus-eluting(SES) and TaxusTM paclitaxel-eluting stents(PES) are known to have similar clinical and angiographic outcomes. We analyzed all patients who received SES or PES retrospectively. Methods; A total of 949 patients who underwent either SES or PES implantation in our hospital from January 2003 to December 2005, evaluated by medical records and vital statistics supplied by statistics Korea. Primary endpoint was a composite of all cause death, myocardial infarction, target lesion revascularization and target vessel revascularization during 5 years after the procedure. Results: During 5years after the procedures, the primary end point occurred in 248 cases(26.1%), where composite end point(SES 27.6% vs PES 22.7% p= 0.31) death(SES 16% vs PES 10.8%, p=0.04 ) were observed in SES and PES group respectively. Conclusion; Despite of rather higher rate of death, which is because it was all cause death, especially in SES group, Clinical outcome did not show much differences in SES and PES group.