| 김계훈, 김희정, 오춘순, 최승희, 윤현주, 홍영준, 김주한, 안영근, 정명호, 조정관, 박종춘, 강정채 |
Background and Objectives: The aim of this study was to investigate the prevalence and predictors of true hypertension (HT) on 24 hour ambulatory blood pressure (AMBP) monitoring who suspected HT on office BP measurements. Methods: A total of 176 patients who suspected HT on office BP measurements were divided into 2 groups; HT on AMBP (true HT group, n=116, 66 males, 47.6±15.4 years) vs no HT on AMBP (pseudo-HT group, n=60, 21 males, 52.3±15.4 years). The definition of HT on AMBP was 24 hour mean systolic BP more than 135 mmHg or diastolic BP more than 85 mmHg in the present study. Clinical, laboratory, electrocardiographic (ECG), pulse wave velocity (PWV), and pulse wave analysis (PWA) related variables were compared. Results: HT on 24 AMBP was observed in 116 patients (65.9%). The history of diabetes mellitus (10.4% vs 1.7%, p=0.037) and male gender (56.9% vs 35.0%, p=0.006) was significantly prevalent in true HT group than in pseudo-HT group. Among laboratory tests, the level of uric acid was significantly elevated in true-HT group than in pseudo-HT group (5.2±1.5 vs 4.5±1.2 mg/dL, p=0.004). The ECG evidence of left ventricular hypertrophy was significantly higher in true HT group than in pseudo-HT group (48.3% vs 28.3%, p=0.008). Brachial-ankle PWV was significantly faster in true-HT group than in pseudo-HT group (1521.8±273.8 vs 1410.8±253.0 cm/sec, p=0.01), but heart-femoral PWV and augmentation index were nor different between the groups. Conclusion: The present study suggested that the prevalence of pseudo-HT was not infrequent in clinical practice, and the patients with DM, male gender, higher uric acid level, ECG evidence of left ventricular hypertrophy, and higher brachial-ankle PWV may have higher chance of true HT.
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