Objective: The aim of this study is to evaluate the predictors of coronary stent fracture (SF) in the patients treated with closed-cell designed stent including sirolimus-eluting stent (SES) and its bare-metal platform, Bx velocity stent (BVS). Background: Various mechanical factors have been considered to be the predictors of SF especially in patient treated with SES. However, it is unknown whether SES is more prone to fracture compared to its bare-metal platform, BX Velocity stent. Methods: We retrospectively analyzed 391 lesions treated with SES or BVS in 339 patients underwent follow-up coronary angiography. Results: Total 30 SFs (7.7%) in 28 patients treated with 29 SES (96.7%) and 1 BVS (3.3%) were found. On univariate analyses, SF was related to the angulated lesion (> 45��) during diastole, longer stent, larger number of stents per lesion (p < 0.001), right coronary artery (RCA) placement (p = 0.008), and SES (p = 0.016). On the multivariate analyses, however, angulated lesion (OR 6.73, 95% CI 2.71-16.71, p < 0.001) and RCA placement (OR 2.82, 95% CI 1.03-7.72, p = 0.044) served as the independent predictor of SF while SES (p = 0.080) and total stent length (p = 0.069) showed only a trend without statistical significance. Conclusions: This study showed that fracture of SES or BVS with same closed-cell typed platform was related to the angulated lesion and RCA placement, but SES itself was not an independent predictor of SF.