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ȣ - 530866 102 |
Comparison of Late Outcomes of Planned Follow-up with Ischemic-driven Follow-up Coronary Angiography after Percutaneous Coronary Intervention with Drug Eluting Stent
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가톨릭대학교 의과대학 순환기내과 |
정종원, 이만영, 황희정, 이재범, 최윤석, 박철수, 윤호중, 정욱성, 승기배, 김재형 |
Backgrounds: Planned follow-up coronary angiography (F/U CAG) led to a 1.7 times higher reintervention rate compared to ischemic-driven F/U CAG in bare metal stent era. However, it is still unclear whether planned F/U CAG after percutaneous coronary intervention (PCI) with drug eluting stent (DES) influences late outcome.
Objective: This research was to study the effect of planned F/U CAG vs. ischemic-driven F/U CAG on late clinical outcome after PCI with DES.
Methods: From November 2004 through December 2008, a total of one hundred patients (M:F=55:45, mean age=65.4±11.9) were enrolled among the 473 patients undergone PCI and F/U CAG. The patients were divided into two groups; planned F/U CAG group (group 1, n=87, M:F=49:38, mean age=65.0±12.4) vs. ischemic-driven F/U CAG group (group 2, n=13, M:F=6:7, mean age=67.9±7.2). Planned F/U CAG was defined as CAG without angina and ischemic-driven F/U CAG was defined as CAG performed due to recurrent angina. We compared major adverse cardiac events (MACE) and reintervention rate between both groups.
Results: There were no significant differences in clinical and angiographic characteristics between both groups. The mean follow-up duration was 256±142 days in group 1 and 354±326 days in group 2 (p=0.302). The rate of MACE in group 2 was higher than the group 1 (64.3% vs. 19.8%, p=0.001) (see Table). Reintervention rate in group 1 was higher than group 2 (53.8% vs. 20.7%, p=0.01). But the all cause mortality was not different between two groups.
Conclusions: Planned F/U CAG reduces the incidence of MACE and leads to an increased reintervention rate compared with ischemic-driven F/U CAG.
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Group 1 |
Group 2 |
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(Planned F/U CAG) |
(Ischemic-driven F/U CAG) |
p Value |
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n=87 |
n=13 |
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Major adverse cardiac events |
17 (19.5%) |
8 (61.5%) |
0.001 |
Death |
0 (0) |
0 (0) |
NS |
Myocardial infarction |
0 (0) |
0 (0) |
NS |
TVR |
4 (4.6%) |
0 (0) |
NS |
TLR |
8 (9.2%) |
3 (23.1%) |
NS |
Non-culprit TVR |
5 (5.7%) |
5 (38.5%) |
NS |
TVR; target vessel revascularization, TLR; target lesion revascularization
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