| ǥ :
|
ȣ - 530795 269 |
| Computed Tomographic Analysis of Pulmonary Vein Thickness in Subjects with and without Atrial Fibrillation |
| 가톨릭대학교 순환기내과 |
| 장성원, 권범준, 최민석, 김동빈, 신우승, 조은주, 김지훈, 진승원, 오용석, 이만영, 노태호, 김재형 |
Introduction
The pulmonary vein has been recognized as the most important arrhythmogenic foci that trigger atrial fibrillation (AF). It was demonstrated that patients with AF have longer and thicker myocardial extension into PVs in human autopsy study.
We aimed to investigate whether the myocardial thickness measured by computed tomography (CT) is different between patients with and without AF.
Method
Multidetector spiral CT of 107 patients (73.8% men, mean age 58± 11 years) with drug refractory AF and 58 control subjects (48.3% men, mean age 52 ± 13 years) were analyzed.
PV thickness was measured in the ostial area of each PVs.
Results
The PV thickness in the patient and control groups was listed in table 1. The PVs at ostial areas were significantly thicker in the patient group than in the control group. Superior PVs were significantly thicker than inferior PVs in both groups (p<0.001).
Conclusion
Patients with a history of AF were found to have thicker PVs than in those without AF and this finding may have implications for the catheter ablation of AF.
|
|
Table 1. Thickness of pulmonary veins measured by computed tomography in subjects with and without atrial fibrillation
| Thickness (mm) |
AF patients (n=107) |
Control group (n=58) |
P value |
| RSPV |
0.42 ± 0.09 |
0.39 ± 0.06 |
0.048 |
| RIPV |
0.30 ± 0.08 |
0.26 ± 0.06 |
0.014 |
| LSPV |
0.42 ± 0.09 |
0.37 ± 0.05 |
<0.001 |
| LIPV |
0.34 ± 0.07 |
0.30 ± 0.07 |
0.008 |
RSPV: right superior pulmonary vein, RIPV: right inferior pulmonary vein, LSPV: left superior pulmonary vein, LIPV: left inferior pulmonary vein
|
|
|
