Paradoxical embolism in the presence of PFO is a well-established possible mechanism responsible for ischemic stroke in patients with no other obvious cause. We report a case of pulmonary embolism after transcatheter closure of patent foramen ovale A 55-year-old woman who had been receiving follow-up monitoring from the department of neurology due to acute infarction of the left MCA shown in brain MRI, was admitted to our hospital for the development of dysarthria and right-sided weakness, and stroke reccurrence was found in brain MRI The 2D echocardiogram also revealed a PFO aneurysm with a 13.5 mm diameter, and the result of the bubble test in which TEE was performed during valsalva maneuver was strongly positive. The patient was referred to the pediatrics department and underwent closure using an 18-mm PFO amplatzer occluder. The result of the air bubble test that was performed after the closure was negative. The patient underwent follow-up checkup and was admitted again via ER with dyspnea five months after the closure. The 2D echocardiogram revealed severe pulmonary HTN and RV dysfunction with tricuspid regurgitation. Neither thromboembolism nor shunt was observed in the PFO amplatzer occluder. Acute pulmonary embolism, however, was found in the chest CT angiography. Heparin protocol was performed, and the symptom improved two days after the patient���s admission. Extremity sonographic Doppler was performed to identify the cause of the pulmonary embolism, but no deep vein thrombosis was found. No embolic sources were found either in the abdominal pelvic CT. The patient had a slight sequele, and no RV dysfunction was observed in the 2D echocardiogram. .We have experienced a case where pulmonary embolism occurred after PFO occlusion, but the cause of the embolism was not identified. It is believed, however, that the pulmonary embolism occurred without stroke reoccurrence because PFO occlusion was performed on the patient with stroke reccurrence Keywords: patent foramen, cryptogenic stroke, pulmonary embolism