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The Distribution of Coronary Artery Calcification in Asymptomatic Korean People
삼성서울병원 건강의학센터
조수진, 조성원, 성지동
BACKGROUND Coronary artery calcification (CAC), a marker for atherosclerosis, is different according to ethnicity. However, the Korean data is a little. METHODS CAC was measured by multi-detector CT in 7832 asymptomatic subjects without history of ischemic heart disease (mean age 52.1 ± 8.2 years, male 84.9%) for screening subclinical atherosclerosis. RESULTS The distribution of Agatston, volume and mass scores according to sex and age were shown in Table1. After controlling age and sex, hypertension (OR 2.05, CI 1.81-2.30,p<0.001), diabetes (OR 1.41, CI 1.13-1.80,p=0.002), hyperlipidemia (OR 1.34, CI 1.19-1.50,p<0.001) and BMI (OR 1.02, CI 1.00-1.04, p=0.033) were independent predictors of CAC presence in multivariate analysis. CONCLUSIONS This is the largest data of CAC distribution measured by Agatston, volume and mass score in asymptomatic Korean people. It will be helpful to interpret CAC in the field of primary prevention.

Age

40 (n=354)

41-50 (n=3337)

51-60 (n=2972)

61-70 (n=999)

>70 (n=170)

Sex

M(n=311)

F(n=43)

M(n=2973)

F(n=364)

M(n=2457)

F(n=515)

M(n=775)

F(n=224)

M(n=131)

F(n=39)

Prevalence of CAC(%)

8.7

2.3

23.8

4.9

42.5

19.2

64.6

46.9

83.2

82.1

Agatston score

Minimum/maximum

0/448.6

0/1.2

0/878.8

0/200.7

0/3991.0

0/681.0

0/2325.8

0/1020.6

0/5002.0

0/2260.0

Mean±SD

5.0±33.8

0.03±0.18

12.9±53.1

1.9±13.1

44.6±153.6

10.3±49.3

116.2±266.4

40.8±105.0

297.5±760.0

183.1±377.7

Volume score

Minimum/maximum

0/309.9

0/1.2

0/3085.0

0/126.6

0/3008.8

0/570.0

0/1925.8

0/1026.4

0/3793.0

0/1750.0

Mean±SD

3.6±24.3

0.03±0.18

11.5±75.2

1.5±10.9

36.0±135.0

7.8±40.1

87.0±202.4

30.3±89.5

206.4±505.2

139.8±297.2

Mass score

Minimum/maximum

0/89.7

0/1.2

0/341.0

0/35.1

0/666.3

0/36.9

0/540.6

0/192.4

0/256.4

0/111.5

Mean±SD



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