Background: The prognostic significance of stenting-related myocardial injury is still controversy. Also, the incidence of periprocedural myocardial infarction (PPMI) remains unclear and evaluation of periprocedural clinical/angiographic characteristics has failed to reliably predict the likelihood of PPMI. Methods: Consecutive 1591 patients, who underwent elective percutaneous coronary intervention with stent(excluded AMI) since March 2003 to July 2007, were stratified into 2 groups based on PPMI. PPMI was defined as 3 times more CK-MB elevation than normal value after PCI. The clinical and angiographic variables associated with PPMI and prediction model for PPMI were analyzed. Results: Overall incidence of PPMI was 9.4% in this registry. PPMI was more frequently developed in female gender(p=0.036), elderly(p=0.001), DM(p=0.044), hyperlipidemia(p=0.004), unstable angina(UA) rather than stable angina(SA)(p=0.001), total stent number(p<0.001), total stent length(p<0.001) and vessel disease number(p=0.01). One year clinical follow-up was available in 96.8%. One year MACE rate was significantly higher in CK-MB elevated group(10.7%vs.5.5%;p=0.011). See the below table for the details. Hyperlipidemia(HR 1.94;95% CI 1.26-3.0;p=0.003), UA rather than SA(1.71;1.20-2.42;0.003), total stent number(1.18;1.03-1.35;0.016), elderly(1.03;1.01-1.05;0.004) and total stent length(1.02;1.01-1.03;0.001) were independent predictors of PPMI. Conclusion: The incidence of PPMI after stent implantation was relatively higher than expected. PPMI can affect to adverse cardiac events. According to our cohort, hyperlipidemia, UA rather than SA, total stent number, age and total stent length were independent predictors for PPMI.