Background: Data are limited about independent predictors for long-term mortality in patients undergoing coronary artery bypass grafting (CABG) for unprotected left main coronary artery (ULMCA) disease. Methods: Between Jan, 2000 and June, 2006, a total of 1170 patients with ULMCA stenosis who underwent CABG were enrolled from 12 academic centers in Korea. Primary outcome was all-cause mortality. Results: During long-term clinical follow-up (median 41.8 months, IQR 26.6-59.7), 82 patients died with 3-year cumulative incidence of 6.4%. After multivariable Cox regression analysis, use of calcium channel blocker, presence of diabetes, ST-segment elevation myocardial infarction (STEMI), Euroscore (쨀6), anastomosis to left anterior descending artery (LAD), and old age were identified as independent predictors for all-cause mortality (Table). Conclusions: In patients with surgical revascularization for ULMCA disease, several clinical (age, diabetes, STEMI, Euroscore) and operative characteristics (anastomosis to LAD, Euroscore) were identified as major determinants for long-term mortality.