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Left atrial size as a predictor of cardiovascular events in patients with hypertrophic cardiomyopathy
한림대학교 의료원 강동성심병원 심장혈관센터¹
최현희¹, 박대균¹, 김성은¹ , 이준희¹ , 한규록¹, 오동진¹
Background: There have been many studies about predictors of sudden cardiac death in hypertrophic cardiomyopathy (HCMP). Less is known about relating factors of cardiovascular events in HCMP. Methods: We retrospectively reviewed 81 patient (male 50; mean age 59±16 years) with HCMP between 1990 April and 2008 January who visited Kang Dong Sacred Heart Hospital. We reviewed clinical characteristics, comorbidities, previous cardiovascular event, presence of readmission, causes of readmission and basic echocardiographic parameters. The cardiovascular events included myocardial infarction (MI), congestive heart failure (CHF), angina, cerebrovascular accident (CVA), and arrhythmia . Results: Of the total 81 patients with HCMP, 15 (18.5%) patients were rehospitalized due to cardiovascular events, during a mean follow-up of 18.6 ± 28.3 months. The causes of rehospitalization were MI (20.0%, 3 of 15), angina (6.7%), CHF (26.7 %), CVA (26.7%) and arrhythmia (20.0%). Among echocardiographic and clinical parameters, left atrial (LA) diameter was significantly larger in patients with cardiovascular events than in those without events (44.1 ± 8.3 mm vs. 37.1 ± 6.5 mm, p=0.001). There was no significant difference in LA diameter between the patients with atrial fibrillation (AF) and the patients without AF (42.5±9.8 mm and 37.2±6.0 mm respectively, p=0.4). The left ventricular wall thickness and the presence of family history of sudden cardiac death were not statistically different between the patients with cardiovascular events and without events (interventricular septal wall thickness, 18.3±5.4 mm versus 16.8±4.5 mm; posterior wall thickness, 13.7±3.3 mm versus 11.6±2.4 mm). Conclusions: LA diameter might be a prognostic factor of cardiovascular events in patients with HCMP.


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