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ǥ : ȣ - 510796   349 
Clinical Implications of Drug-Eluting Stent Fracture
영남대병원 순환기 내과¹ , 계명대학교 동산병원 순환기 내과² , 인제대학교 부산백병원 순환기 내과³
김웅¹, 박종선¹ ,이상희¹ ,홍그루¹ ,조윤경² ,남창욱² ,허승호² ,김윤년² ,김두일³ ,양태현³ ,최상분³ ,설상훈³
Purpose and objectives : Stent fracture (SF) has been suggested as a cause of restenosis and cardiac events after sirolimus-eluting stent (SES) implantation. But, we don’t have any data about it’s prognosis and optimal therapeutic strategies. We have performed this study to evaluate the clinical outcomes of SES fracture. Methods : A total of 52 SFs from 42 consecutive patients who were implanted with SES in 4 centers were included in this registry. All therapeutic modalities (no treatment, balloon angioplasty, stent) were decided by the operator’s decision. Patients were followed up to evaluate major adverse cardiac events such as death, myocardial infarction and repeat revascularization. Follow up angiography was performed in selected patients. Results : Average SF number was 1.2 per patients. Mean follow up duration from stent implantation to Fx detection was 277±153 days. SF was found with restenosis in 19 of 52 SF lesions (37%). Ten patients (24%) presented with chest pain and 9 of them showed restenosis associated with SF. Twenty seven patients (62%) were treated by medically and 15 patients (38%) were treated by intervention (stent 10, balloon 5). At long term follow up (469±291 days), total 5 MACE have occurred. Four patients (15%) had myocardial infarction, and 3 of these were related with very late stent thrombosis in medication arm. Otherwise, only 1 patient (7%) had TLR without myocardial infarction in PCI arm. No death was found. Conclusions : SF, even if it’s silent, is not safe and careful examination to find out the SF and closed attention for the cardiac events are needed.


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