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ȣ - 510432 341 |
Arterial Dysfunction is Significantly Associated with Abnormal Blood Pressure Response during Treadmill Exercise Test |
전남대학교병원 심장센터 |
김계훈, 나영자, 이수진, 오춘순, 최승희, 윤현주, 윤남식, 문재연, 홍영준, 박형욱, 김주한, 안영근, 정명호, 조정관, 박종춘, 강정채 |
Backgroud and Objectives The aim of this study was to investigate impacts of arterial dysfunction on hemodynamic changes during treadmill exercise test. Methods A total of 113 patients (52.5±10.3 years, 60 males) who underwent treadmill exercise test (TMT) using modified Bruce protocol were divided into two groups according to the pre-exercise heart-femoral pulse wave velocity (HFPWV); high HFPWV group (group I: 60 patients, 50.2±10.9 years) vs low HFPWV group (group II: 53 patients, 56.1±8.9 years). Hemodynamic responses at each stages and maximal blood pressure (BP) and rate pressure products (RPP) were compared between the groups during TMT. BP and RPP recovery within 2 minutes were also compared between the groups during the recovery stage of TMT. Results Group I showed significantly elevated BP response at 3 minutes of TMT than in group II; systolic BP (132.2±10.9 vs 117.4±15.2 mmHg, p=0.001), diastolic BP (77.5±14.2 vs 69.1±9.7 mmHg, p=0.002), RPP (121.1±35.6 vs 103.1±19.6, p=0.006). Maximal systolic, diastolic BP, and RPP were also significantly higher in group I than group II; systolic BP (172.7±26.4 vs 149.0±25.1 mmHg, p<0.001), diastolic BP (78.6±15.7 vs 72.3±12.0 mmHg, p=0.04), RPP (216.0±69.8 vs 189.4±61.0, p=0.04). BP and RPP recovery within 2 minutes were also significantly delayed in group I than in group II; systolic BP (158.2±15.4 vs 136.3±23.2 mmHg, p<0.001), diastolic BP (75.8±15.4 vs 67.9±11.9 mmHg, p=0.013), RPP (173.1±52.9 vs 133.3±55.5, p=0.001). Conclusion The results of this study suggested that arterial dysfunction is a significant predictor of abnormal BP response during TMT and delayed recovery of BP following exercise.
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