Purpose: Large artery stiffness has been recognized as an independent risk factor for cardiovascular disease. Augmentation index (AI) and pulse pressure (PP) from peripheral arterial and central aortic waveform has been considered as a reliable marker for atherosclerosis. However, the reference value for AI and PP was not established in Korea. So, the aim of this study was to define the diagnostic thresholds of AI and PP from peripheral arterial and central aortic waveform for subjects in Korea. Methods: We randomly recruited 522 subjects (mean age 43.6  9.6 yrs, male 290(55.6%), smoker 145(27.8%)) without hypertension, diabetes and previous or concomitant cardiovascular disease. We measured body mass index(BMI), peripheral blood pressure (BP), and PP(PPp) and calculated peripheral AI(AIp), central BP, central PP(PPc), and central AI(AIc) by using automatic device(Gaon 21A system, Hanbyul, Jeonju, Korea). We rounded the 95th prediction bands to determine diagnostic thresholds of PPp, AIp, PPc, and AIc. Results: The PPp, AIp, PPc, and AIc significantly increased with age. The PPp and PPc were positively related to BMI. The AIp and AIc in female were significantly increased compared to male. The 95th predictions bands of this relation at age 40 years, approximated to 70 mmHg for PPp, 50 mmHg for PPc, 100% for AIp, and 40% for AIc. Conclusions: The measurement of PP and AI might be simple, useful markers for stratification of cardiovascular disease.