Purpose; The purpose of this study was to identify factors contributing to postoperative feeding difficulties in neonates following cardiac surgery. Methods; A retrospective cohort study used chart audit of 311 consecutive infants who underwent cardiac surgery. Ten variables were analyzed as possible predictors of postoperative feeding difficulties including; diagnosis, demographics, details of surgery and postoperative course. Results; Mean patient age was 40.3days(range; 2~111days) and mean patient body weight was 3.87kg(range; 1.3~7.7kg). At hospital discharge, 266(84.6%) infants were orally feeding and 45(14.4%) were not. Overall mean hospital length of stay was 18.0(짹14.5) days. Mutilvariate logistic regression analysis revealed ICU length of stay(odd���s ratio 4.57, 95% CI 1.93-10.96), length of postoperative intubation(odd���s ratio 1.73, 95% CI 0.74-4.06), weight at surgery(odd���s ratio 1.68, 95% CI 0.77-3.68), surgical intervention(arch surgery versus no arch surgery)(odd���s ratio 0.37, 95% CI 0.17-0.80) as independent predictors of failure to feed orally at discharge from hospital. Conclusion; Risk factors for feeding difficulties in the postcardiac surgery infant are long ICU stay, prolonged intubation, low weight at surgery and arch involving surgery. Early identification of neonates at risk for feeding difficulties may lead to development of strategies to reduce morbidity, improve patient care and provided better resource utilization.