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ȣ - 500080 77 |
Complex Lesion Type and low TIMI Flow Are Associated with Stent Thrombosis After Taxus Stent Implantation |
전남대학교병원 심장센터, 광주원광대학병원 |
김인수, 정명호, 박수환, 김정훈, 이두환, 최옥자, 정민아, 박현아, 윤남식, 황선호, 홍영준, 김주한, 안영근, 조정관, 박종춘, 강정채, 박옥규 |
Background : Major concerns have been raised regarding the stent thrombosis (ST) after drug-eluting stent (DES) implantation. It is uncertain that the relationship between the ST rate and paclitaxel-eluting Taxus stent implantation.
Methods: The consecutive 1,749 patients (62.4±10.9 years) were deployed Taxus stent (1,964 stents) in the coronary artery lesions between March 2003 and July 2006. Out of 1,749 patients, 15 patients (0.80%) developed angiographically proven ST. Clinical and angiographic characteristics of the patients were analyzed.
Results : One patient suffered from acute ST (6.6%) and 8 patients subacute ST (53.3%) and 6 patients late ST(40.0%). Fourteen patients were male. Clinical diagnosis were AMI in 7 patients (46.6%) and unstable angina in 6 patients (33.3%). Target lesion location was left anterior descending artery in 8 patients (53.3%). Risk factors were smoking in 12 patients (80.0%) and diabetes in 4 patients (26.6%). Lesion characteristics were in-stent restenosis lesion (2 patients, 13.3%), bifurcation lesion (7 patients, 46.6%), and chronic total occlusion (13 patients, 86.6%). There was no ST in overlapped TAXUS stents. The B2/C lesion according to ACC/AHA classification and TIMI flow less than II before stenting were demonstrated in 13 patients (86.6%). Mean stent size and length was 3.2±0.4 mm and 28.8±4.9 mm, respectively. Among these 15patients, one patient died and 14 patients had non-fatal Q-MI.
Conclusion : ST rate of Taxus stent was relatively low, but complex lesion type was associated with ST after Taxus stenting.
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