Backgrounds and objective: Even though the incidence and prevalence of ST segment elevation myocardial infarction (STEMI) in Korean is growing manner, there is no large, population based clinical characteristics and risk factor analysis data of STEMI. To obtain basic clinical characteristics of Korean STEMI patients(pts), we analyzed clinical characteristics and major adverse cardiac events (MACE) and its risk factors from Korean Coronary Artery Disease Registry.
Design and Methods: KCAR have filed up clinical baseline characteristics and follow-up data of 5000s Korean adult pts who have been done coronary angiography, prospectively in national-wide spread 7 university hospitals. We have analyzed baseline characteristics and MACE data, which have been composed of death, reinfarction, target vessel revascularization (TLR) and compared risk factors between MACE and non-MACE pts, death and survived pts.
Results: 697 pts (M:F = 521:176) suffered STEMI during follow-up period. STEMI occurs chronologically late in females, significantly (69.8±9.5 yrs vs 59.4±11.9 yrs, p < 0.0001). General risk factors distribution is diabetes (157, 22.5%), hypertension (280, 40.3%), smoking (356, 51.1%), hyperlipidemia (58, 8.3%), HDL-C < 40 mg% (171, 24.5%), premature CHD familial history (14, 2.0%), and prior CVA (30, 4.3%). Male pts frequently affected in diabetes (25% vs 15%, p=0.005). BMI is 24.3±3.0 in male and 23.9±3.4 in female. Major Killip classes on admission were I (62.0%) and II (23.45). Clinical follow-up were checked in 359 pts (51.6%) during 191.3±117.0 days. MACE occurred in 43 pts(11.97%, 13deaths, 1 reinfarction and 29 TLRs). There in no significant risk factor differences in MACE vs non MACE pts and between death and survived pts. Conclusion: In 5000s pts in KCAR, 697 pts suffered STEMI. STEMI occurs younger age group in male than female. Major risk factors for Korean STEMI pts are smoking, hypertension, low HDL-C and DM. Mean BMI in STEMI was less than 25. For more detail risk analysis, prolonged follow-up is essential.
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