Background: Myocardial viability may influence the diastolic function of left ventricle reflecting chamber remodeling in early phase after acute myocardial infarction(AMI). However there was few reports about that relationship in human. In this prospective study, we aimed to evaluate whether myocardial viability by strain rate imaging has an influence on left ventricular end diastolic pressure(LVEDP) in selected patients in the early phase after AMI. Methods: Twenty-four consecutive patients with AMI and akinetic wall motion in at least one segment by baseline echocardiography underwent low-dose dobutamine echocardiography(LD-DSE; upto 10mcg/kg/min) to assess myocardial viability on 5~9 days after event. Myocardial viability was quantitatively evaluated by change of peak systolic strain rate(psSR), percent change of time to onset of regional relaxation(TR) and wall motion score index(WMSI). Various echocardiographic parameters was measured on the study. And at the same day just after LD-DSE, left heart cathrterization with recording of LVEDP was performed. Results: Patients(68% Male; mean age 62짹13 years) showed mildly decreased LV systolic functions(EF=45.8짹10.8%) and elevated LVEDP(25.3짹9.0mmHg). The percent change of TR showed distinct, but statistically insignificant linear correlation with LVEDP(r=0.40, p=0.10), but change of psSR and WMSI didn't. And interestingly, percent change of TR also showed distinct but statistically insignificant linear correlation with the difference of pulmonary venous atrial flow reversal duration and mitral A wave duration(r=0.44, p=0.07), but other parmeters testing myocardial viability didn't show significant correlations with noninvasive diastloc parameters. Conclusions: Myocardial viability may have an influence on left ventricular end diastolic pressure(LVEDP) in patients in the early phase after AMI.