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ȣ - 530777 103 |
| Cardiovascular risk factors and hospital mortality among patients with ST elevation and non-ST elevation myocardial infarction from the Korea Acute Myocardial Infarction Registry |
| 경북대학교병원 순환기 내과¹ , 영남대학교병원 순환기 내과²,전남대학교병원 순환기 내과³ , 대구가톨릭대학교병원 순환기 내과⁴ , 계명대학교병원 순환기 내과5 , 충남대학교병원 순환기 내과6 , 부산대학교병원 순환기 내과7 , 충북대학교병원 순환기 내과8 ,경희대학교 동서 신의학 병원9 |
| 이장훈¹, 채성철¹ , 이상혁¹ , 배명환¹ , 류현민¹ , 양동헌¹ , 박헌식¹ , 조용근¹ , 전재은¹ , 박의현 ¹ , 김영조² , 정명호³ , 김기식⁴ ,허승호5 ,성인환6 , 홍택종7 , 조명찬8 , 김종진9 |
Background: Little is known about the associations between cardiovascular risk factors and in-hospital mortality among patients with ST-segment elevation myocardial infarction (STEMI) and non-STEMI. We investigated whether cardiovascular risk factors are differently related to STEMI and non-STEMI. We also investigated which cardiovascular risk factors are independently associated with in-hospital mortality in patients with STEMI and non-STEMI. Methods: From the Korean Acute MI Registry, between November 2005 and January 2008, 10,213 eligible patients (7238 males and 2975 females; mean age=64.9 ± 12.5 year-old) were included in this study. Results: Of these patients, STEMI was present in 6172 (60.4%) patients. Patients who smoke were more likely to have STEMI (odds ratio [OR] 1.311, 95% confidence interval [CI] 1.194 to 1.440, p<0.001), whereas patients with diabetes mellitus (OR 0.815, 95% CI 0.743 to 0.895, p<0.001) and hyperlipidemia (OR 0.738, 95% CI 0.645 to 0.845, p<0.001) were less likely to have STEMI after adjustment for confounding variables. Patients with prior disease (myocardial infarction, angina, and revascularization) and treated with anti-platelet drugs or angiotensin converting enzyme inhibitors before admission were also less likely to have STEMI. The in-hospital mortality was significantly higher in patients with STEMI (4.7% versus 3.0%, p<0.001). Among cardiovascular risk factors, previous cerebrovascular disease (OR 2.741, 95% CI 1.062 to 7.075, p=0.037) was independently associated with increased risk of in-hospital mortality in patients with STEMI, whereas previous angina (OR 2.698, 95% CI 1.127 to 6.458, p=0.026) was independently associated with increased risk of in-hospital mortality in patients with non-STEMI after adjustment for confounding variables Conclusions: Smoking is strongly associated with STEMI, whereas diabetes mellitus and hyperlipidemia are associated with non-STEMI. Cardiovascular risk factors are also differently related to in-hospital mortality in patients with acute MI.
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