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Clinical Presentation of Newly Diagnosed Acute Decompensated Heart Failure In the Elderly Patients
연세대학교 의과대학 세브란스 심장혈관병원 심장내과
문정근, 강석민,조인정,심재민,이상학,장양수,정남식
Background: The elderly population (≥65 years old) is increasing and the incidence and prevalence of congestive heart failure escalates with age. However, clinical characteristics of elderly patients (pts) (EPs) with newly diagnosed - acute decompensated heart failure (ND-ADHF) are not clarified yet. The aim of this study is to determine the characteristic initial presentation of ND-ADHF of the EP compared with non-elderly pts (NEPs). Methods and Results: Two hundred fifty six pts (153 male pts) who admitted to our hospital between January 2005 and March 2009 due to ND-ADHF were investigated. The clinical characteristics and echocardiographic parameters were analyzed in the EPs (mean age 74.0±6.9 years old) and NEPs (mean age 50.6±10.8 year old). In intergroup comparison, body mass index (22.3±4.5 vs. 24.0±4.4 kg/m2), estimated glomerular filtration rate (54.8±24.3 vs. 69.2±30.7 ml/min/m2), C-reactive protein (28.5±46.9 vs. 7.6±11.6 mg/dL) and hemoglobin (12.3±2.1 vs. 13.6±2.3 mg/dL) level were significantly different (p<0.05). The left ventricular end-diastolic diameter (LVEDD) and end-systolic diameter (LVESD) were significantly less dilated (LVEDD: 57.6±11.3 vs. 62.0±10.9 mm and LVESD: 48.1±11.1 vs. 52.1±11.7 mm) in EPs (p<0.05) than those of NEPs. However, diastolic dysfunction was more severe in EPs (E/E’: 21.7±9.4 vs. 18.0±8.9; E’: 4.0±1.3 vs. 5.2±1.9 cm/sec than NEPs (p<0.05). Conclusion: The EPs with ND-ADHF have different clinical characteristics compared with NEPs and diastolic dysfunction is more problematic than systolic dysfunction in these pts.


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