Purpose : Homografts are one of the option among the variable conduits that have been used for right ventricular outflow tract(RVOT) reconstruction. We sought to determine late patient outcome and risk factors for homograft failure. Methods : Between December 4, 1992 and August 11, 2008, 136 patients received cryopreserved homografts for RVOT reconstruction. We retrospectively reviewed patient���s record. There were 89 males(65.4%). 63 aortic(46.3%) and 69 pulmonic(50.7%) homografts were used. Mean homograft conduit size were 19.4짹5.0mm. Median body weight and age at the operation were 13.5 kg (2.4 - 85 kg) and 39 months (6 days - 61 years), respectively. Most common diagnosis was pulmonary atresia with VSD (n=86, 63.2%). Results : There were 10 early deaths(7.4%) and 7 late deaths(5.6%). Excluding early deaths, there were 53 reoperations(39%) and their mean follow-up durations were 85짹43.2 months(2¬¬ – 177 months). Actuarial survival rate at 1year, 3years, 5year and 10years were 89.7%, 88.9%, 88.9% and 85.6% respectively). Univariate and multivariate analysis revealed that bypass time was risk factor for late mortality (p=0.001, p=0.048). Actuarial freedom from reoperation at 1year, 3years, 5years and 10years were 91.1%, 83.9%, 74.5% and 36.5%. Univariate analysis revealed that age at operation (p=0.002), body weight (p=0.001), aortic homografts (p=0.006) and homograft conduit size (p=0.001) were risk factors for reoperation. After adjustment, however, only body weight (p=0.004) were risk factors reoperation. Conclusions : The homograft showed acceptable reoperation rate during 5years after operation. After 5years, however, the durability of homograft decreaed significantly.