Background: The mortality of acute myocardial infarction (AMI) patients has been known to be increased as the time between symptom onset and hospital arrival. But the relationship of AMI mortality and the distance between home and hospital is not well known. Methods: During 2005Nov to 2007 Dec, 1,223 AMI patients (63.2짹12.3 years old, 864 males) were classified by the distance between home and hospital, within 1 hour (group 1, n=699), 1 to 2 hours (group 2,n =315), 2 to 3 hours (group 3, n=199), over 3 hours (group 4, n=9). The mortality, success rate of percutaneous coronary intervention (PCI), major adverse cardiac event (MACE) at 1 month, 6 month, 1 year was compared. Results: Diagnosis of acute ST-segment elevation myocardial infarction (STEMI) were not different among groups (65.4% vs. 65.1% vs. 66.8% vs. 33.3%, p=0.233). Clinical characteristics and angiographic findings were not different among 4 groups. The success rate PCI were higher in near distance group (93.7% vs. 91.3% vs. 89.8% vs. 85.7%, p=0.042). In STEMI patients, more patients had primary PCI as the distance closer (76.1% vs. 77.1% vs. 72.9% vs. 66.7%, p=0.527). In-hospital mortality became higher as the distance longer (4.4% vs. 5.1% vs. 5.0% vs. 11.1%, p=0.504). one-month composite MACEs became higher as the distance longer, but not significant (9.9% vs. 11.7% vs. 10.2% vs. 22.2%, p=0.486). Six-month composite MACEs became higher as the distance longer, but not significant (19.8% vs. 23.5% vs. 17.3% vs. 22.2%, p=0.368). One-year composite MACEs became higher as the distance longer, but not significant (23.3% vs. 26.0% vs. 19.5% vs. 33.3%, p=0.337). One-month mortality became higher as the distance longer, but not significant (7.0% vs. 9.5% vs. 8.7% vs. 22.2%, p=0.141) and one year mortality became higher as the distance longer, but not significant (10.2% vs. 14.3% vs. 9.7% vs. 22.2%, p=0.171). Conclusions: As the distance between home and hospital closer, AMI patients had more primary PCI and had higher success rate of PCI. Although in-hospital and 1-year total MACEs and mortality became higher as the distance longer, but not significant.