Backgrounds.
Electrical DC cardioversion for atrial fibrillation (AF) is the most effective method for the restoration of sinus rhythm. There is evidence that inflammation might contribute to the development and recurrence of atrial fibrillation (AF). The aim of this study is to evaluate various parameters as predictors of AF recurrence in patients with successful sinus conversion.
Methods.
45 patients with a history of symptomatic AF underwent cardioversion. Echocardiography, brain natriuretic peptide (BNP) measurement and Hs-CRP assay were performed prior to cardioversion. During one week follow up , 13 patients ( 29% ) had recurrence of AF. AF recurrence was associated with significantly higher pre-Hs-CRP levels. (success Vs recurrence group : 0.16±0.18, 0.58±0.84 mg/L p=0.045 ) LA diameter and BNP was not significantly different between two groups. (LA diameter : 4.3±0.7 Vs 4.7±0.4 cm , BNP : 216±189 Vs 326±337 pg/ml)
Conclusion.
Our data implies that high levels of CRP are associated with an increased risk of recurrence of AF.
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