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Clinical Significance of Early Recurrences of Atrial Tachycardia After Atrial Fibrillation Ablation: Long-term Outcomes of Late Recurrence
고려대학교 안암병원 심혈관 센터¹, Utah Valley Medical Center, Provo, UT, USA²
최종일¹, 박희남¹, 장진근¹, 박재석¹, 곽재진¹, 김용현¹, 신승용¹, 임홍의¹, Chun Hwang², 김영훈¹
Background: Early recurrences of atrial tachycardia (ERAT) commonly developed after radiofrequency catheter ablation (RFCA) for patients with atrial fibrillation (AF). However, the long-term outcomes of ERAT have not been clearly elucidated, and it remains to be determined whether ERAT predicts late recurrence of AF or AT. Methods: Of 353 consecutive patients underwent circumferential pulmonary vein (PV) isolation with or without additional linear ablation for AF, ERAT was documented in 56 patients (15.6%). We defined ERAT as early relapse of AT within 3-month period after RFCA. Results: During 21.7±12.5 months, the recurrence rate of AF or AT was higher in patients with ERAT (41.1%) than without ERAT (11.8%, p<0.001). The number of patients taking antiarrhythmic drugs (AAD) was similar between two groups (45.5% vs. 47.8%, p=NS).The duration of ablation (174.3±62.3 vs. 114.7±39.5 min, p=0.046) and the total procedure time (329.3±83.4 vs. 279.2±79.7, p=0.027) were significantly longer in patients with late recurrence than those without late recurrence. The number of patients underwent cavo-tricuspid isthmus (CTI) ablation (73.9% vs. 42.4%, p=0.023, RR:3.8, 95% CI 1.3 to 12.2) and showing AF or AT inducibility (65.2% vs. 36.4%, p=0.036, RR:3.3, 95% CI 1.1 to 9.9) immediately after ablation was greater in patients with late recurrence than those without late recurrence. Among 13 (23.2%) who received repeat procedure in patients with ERAT, the previous ablation lines were reconnected in 11 patients including PV (n=10), roof line (n=4), left lateral isthmus (n=4), and CTI (n=4), and 10 patients (76.9%) were free from AF or AT during 6.3±3.0 months follow-up. Conclusion: The long-term recurrence rate after AF ablation is higher in the patients with ERAT compared with the patients without ERAT, which is associated with prolonged procedure time, CTI ablation, and inducibility of AF or AT after ablation.


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