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The prevalence of left ventricular hypertrophy (LVH) by new ASE-guidelines in Koreans and echocardiographic datas in newly diagnosed LVH group
순천향대학교 부천병원
서혜선, 최재혁, 서존, 조윤행, 이내희
Background: The diagnosis of left ventricular hypertrophy (LVH) has been incorporated as an important marker of cardiovascular disease. The determination of cut off points to define abnormality is frequently controversial, and ASE committee developed the new criteria of LVH at 2005 because traditional cut-off limits may ignore cardiovascular risk associated with increased LV mass in the "normal" range based on statistical assumptions. Objective: We want to know the prevalence of LVH and echocardiographic, clinical meaning after applying this new criterion in Koreans. Methods & results: We enrolled 2489 consecutive subjects during recent 2 years (905 men, 1584 women) who are diagnosed as LVH by echocardiography in our center. Patients with other significant heart problem, systemic disease and poor echo window are excluded. Among these patients, 331 men(37%) and 690 women(44%) who had LV mass below the limits traditionally employed for LVH definition are categorized as LVH by new criteria. The more proportion of non-hypertensive patients is included in LVH group (from 29% to 34% in men, from 29% to 36% in women). Several echocardiographic datas are changed in new LVH group.(Table) Conclusions: By new LVH classification criteria, the prevalence of LVH has increased about 40% in Korean. Further follow up evaluation whether these changes would predict major cardiovascular events better than previous criteria will be needed.

Men

LVH By new criteria

(n=905)

LVH by traditional criteria

(n=574)

P value

Women

LVH By new criteria

(n=1584)

LVH by traditional criteria

(n=894)

P value

Age (years)

56.8 ± 13.8

57.1 ± 14.1

0.748

 

61.5 ± 13.5

63.2 ± 13.1

0.003

Hypertension

66%

71%

0.060

 

64%

71%

0.001

LVEF (%)

63.5 ± 6.7

63.0 ± 7.2

0.130

 

65.6 ± 5.8

65.3 ± 6.0

0.328

LVEDD (mm)

49.7 ± 4.3

50.3 ± 4.5

0.013

 

46.0 ± 3.9

47.0 ± 4.0

<0.001

RWT

0.43 ± 0.08

0.44 ± 0.08

0.003

 

0.41 ± 0.07

0.42 ± 0.08

<0.001

LAVI (ml/m2)

29.1 ± 10.8

31.0 ± 11.7

0.001

 

28.2 ± 11.0

31.1 ± 12.4

<0.001

E (cm/sec)

67.7 ± 19.1

68.2 ± 20.3

0.578

 

68.8 ± 18.6

69.6 ± 19.5

<0.001

E’ (cm/sec)

6.33 ± 1.93

6.04 ±1.92

0.005

 

5.87 ± 1.98

5.50 ± 1.83

<0.001

E/E’

11.4 ± 4.2

12.1 ± 4.5

0.004

 

12.6 ± 4.6

13.6 ± 4.9

<0.001



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