Background: The prevalence of asynchrony in the newly diagnosed, uncomplicated essential hypertension has not been explored. Methods: 45 hypertensive and 15 control individuals underwent following echocardiographic evaluations: (i) total isovolumic time (s/minute, T-IVT, global asynchrnony); (ii) LV filling time/RR interval (FT, global atrioventricular asynchrony); (iii) difference between time form ECG Q to peak velocity of RV free wall and maximally delayed LV segment (ms, DRL, global interventricular); (iv) standard deviation of time from ECG Q to systolic peak velocity of 12 LV segments (ms, Ts-SD12) and maximum difference of time to systolic peak velocity among 12 LV segments (ms, Ts-max, intraventricular systolic segmental); (v) sum of time exceeding aortic closure in strain curves of 12 LV segments (ms, o-ExcT, contractile diastolic); (vi) SD of time from ECG Q to early diastolic peak velocity of 12 LV segments (ms, Te-SD12) and maximum difference of time to early diastolic velocity among 12 LV segments (ms, Te-max, intraventricular diastolic segmental). Results: The prevalence of systolic segmental asynchrony was higher in the hypertensive group (56.7% vs 11.1%, p=0.02, by cut-off 40ms of DRL; 55.6% vs 13.3%, p=0.004, by cut-off 32 ms of Ts-SD12; 46.7% vs 13.3%, p=0.021, by cut-off 100 ms of Ts-max). DRL, Ts-12SD and Ts-max were also greater. conclusions: LV systolic segmental asynchrony was highly prevalent in the newly diagnosed hypertension.