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ȣ - 520303 112 |
Coronary Calcium Scoring by Dual Source CT is Closely Related to Disease Severity and Cardiovascular Risk Factors |
전북대학교 의학전문대학원 순환기내과¹ , 영상의학과² |
이선화¹, 채제건¹ , 진공용² , 송민주¹ , 이강휴¹ , 이상록¹ , 이경석¹ , 김원호¹ , 고재기¹ |
Background: We evaluated the severity of coronary artery disease and clinical characteristics according to coronary calcium score detected by dual source CT (DSCT). Methods: Patients who were undertaken coronary CT angiography (CTA) using DSCT from Nov 2007 to Jun 2008 were divided into 3 groups according to Agatston score: Group I, ≥400 (n=67); Group II, 100-400 (n=91); Group III, <100 (n=98). Results: Patients in the higher Agatston score group were older and more frequently male. The incidence of risk factors was higher and coronary lesions were more severe in the higher calcium score groups (Table). The Agatston score was positively correlated with diseased vessel number on both CTA (r=0.445, p=0.01) and CAG (r=0.376, p=0.01). Conclusion: Patients with higher coronary calcium score measured by DSCT had more severe coronary disease as well as higher incidence of cardiovascular risk factors.
|
Group (Agatston score) |
Group I (≥400)
n=67 |
Group II (100-400)
n=91 |
Group III (<100)
n=98 |
p value |
|
|
|
|
Mean Agatston score |
1172.5±841.4 |
216.1±82.3 |
9.7±23.1 |
<0.001* |
Age (years) |
69±8 |
66±9 |
60±12 |
<0.001* |
Male |
73.1% |
59.8% |
41.8% |
<0.001* |
Significant stenosis on CTA |
71.9% |
61.1% |
11.2% |
<0.001* |
Diseased vessels on CTA |
1.1±0.9 |
0.9±0.9 |
0.1±0.4 |
<0.001* |
CAG performed |
41.3% |
33.0% |
6.0% |
<0.001* |
Diseased vessels on CAG |
2.0±1.1 |
1.6±1.0 |
0.8±0.8 |
0.051 |
Risk factors |
|
|
|
|
Hypertension |
66.7% |
65.5% |
35.4% |
<0.001* |
Diabetes |
31.4% |
27.6% |
15.9% |
0.078 |
Smoking |
63.9% |
37.9% |
15.9% |
<0.001* |
Amount (PG·YR) |
37.9±18.0 |
29.9±12.4 |
27.3±9.0 |
0.038* |
Dyslipidemia |
51.0% |
82.8% |
46.3% |
<0.001* |
History of PAOD |
7.9% |
2.3% |
0% |
0.019* |
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