Background: Uric acid (UA) is one of prognostic markers for poor outcomes in chronic heart failure (HF). However, the prognostic value of UA in acute decompensated heart failure (ADHF) has not been well defined. The aim of this study was to determine the role of UA as a prognostic value for short-term outcomes in the setting of ADHF. Methods: UA, N-terminal Pro B-type natriuretic peptide (NT-ProBNP) and other biochemical markers were obtained on admission from 193 patients (age 69짹13 years, 79 males) with ADHF. Patients were followed for 3 months for major cardiovascular events defines as the composite of cardiac death and re-admission for HF. Results: Of the 193 patients, 23 (11.9 %) died and 5 (3.6%) were re-admitted for HF during follow-up. By univariate analysis, possible predictors of short-term cardiovascular events were uric acid (mean 8.07짹3.02 mg/dl), NT-ProBNP (7406.86짹8513.39 pg/ml,), and creatinine clearance (mean 54.58짹44.98 ml/min). Multivariate Cox hazard analysis demonstrated that UA was independently associated with the increased short-term outcomes (Hazard ratio 1.113, 95% confidence interval 1.004-1.234, p=0.041), whereas NT-ProBNP was not. Conclusion: UA would be a useful independent predictor for short-term outcomes, particularly in patients with ADHF.