Introduction : Thrombosuction by aspiration catheter during primary PCI has been proved to be safe and effective method for coronary reperfusion. However, changes of left ventricular (LV) wall motion after thrombosuction have never been evaluated. Methods : From April 2005 to January 2008, we analyzed 111 patients who were underwent primary PCI with or without thrombosuction and completed Echocardiographic examination on 1st to 5th days (baseline) and 6 to 12 months (follow-up). We divided them into suction group (n=58) and non-suction group (n=53) and then compared two groups by use of LV wall motion score (WMS), WMS index (WMSI) and ejection fraction (EF) were assessed at baseline and follow-up period. WMSI was analyzed and calculated according to 16-segment model. LV EF was measured by modified Simpson���s method. Recovery of wall motion was defined as an improvement in wall motion of ���2 contiguous segments in infarct-related segments between baseline and follow-up. Results: Table Conclusion :Our prospective randomized study shows that primary PCI with thrombosuction may be significant benefit to recovery of regional wall motion in patients with STEMI.