紐⑹�� : The aim of out study was to evaluate the diagnostic accuracy of 64-sliced MDCT coronary angiography according to various clinical status and parameters 諛⑸�� : We studied 91 consecutive patients undergoing invasive coronary angiography. Patients were excluded for severe arrhythmia, but not for high heart rate, severe coronary calcification, or obesity. All vessels were analyzed, including those <1.5mm in diameter. Results were assessed on the per-patient analysis for significant coronary stenosis (over 50% luminal narrowing) as compared to quantitative coronary angiography (QCA). 寃곌낵 : A total of 21% of patients had calcium scores above 400 Agatston U, 23% had heart rates > 80 bpm, and 49% were overweighted. The patient with acute coronary syndrome was 26% and high Framingham risk score (FRS; > 20) was 21%. The sensitivity, specificity, PPV and NPV were 95%, 80.6%, 90.5% and 89.3%, respectively. Based on various parameters, MDCT showed no significant deterioration of accuracy in the presence of severe calcification, and at rates of above 80 bpm. However, in overweighted group (body mass index ��� 25 kg/m2), the diagnostic accuracy was slightly reduced. For the evaluation of diagnostic accuracy by clinical status, there was no significant difference according to FRS or clinical impression of the patients including acute coronary syndrome. 寃곕�� : Our results indicate high diagnostic accuracy of 64-slice MDCT as compared to QCA in a broad spectrum of patients.