Background: The aims of this study were to evaluate the incidence and the clinical significance of myocardial bridging in 265 patients with chest pain examined with 16-row MDCT coronary angiography. Methods: Two hundred sixty-five patients who were referred to Dongsan medical center were involved in this study. These patients had atypical chest pain or symptoms suggestive of coronary artery disease. Patients were premedicated with propranolol and nitroglycerine. ECG-gated CT coronary angiography was performed with a 16-row MDCT scanner (0.37-sec rotation time, 16 �� 0.75 mm detector collimation). Correlation was made between the presences of myocardial bridging on MDCT and the clinical results based on history, examination, and any subsequent clinical workup at the 2-month follow-up. Results: Among the 265 patients, 20 cases (7.5%) of myocardial bridging were detected. All cases of myocardial bridging were located at the middle third of the left anterior descending coronary artery (LAD). Superficial bridging was identified in thirteen patients and deep bridging in seven. The length of tunneled artery was between 5 and 25 mm, with a mean of 15.6 mm, and the depth of tunneled artery was between 1.0 and 5.9 mm, with a mean of 3.1 mm. In five patients among whom 7 patients had deep bridging, myocardial bridging might be associated with chest pain. In thirteen patients, 4 patients might have correlation with myocardial bridging. Conclusions: We found the incidence of myocardial bridging in this patient group to be 7.5 %. This result is higher than most of angiographic studies in the literature. The types of myocardial bridging might be related to the clinical symptom. Our study shows that MDCT is a reliable and sensitive diagnostic tool for diagnosing myocardial bridging. Larger multi-center studies are required to evaluate the incidence of myocardial bridging and to determine which myocardial bridging is responsible for cardiogenic chest pain