Backgrounds : Primary PCI is gold standard for STEMI. However, because of low availability to angioplasty, most patients with STEMI are reperfused with intravenous thrombolysis. Early post-thrombolysis routine deferred PCI has been discouraged due to its association with high incidence of events. We assessed whether clinical outcomes of early deferred PCI after fibrinolytic therapy is comparable to primary PCI in the era of stents and antiplatelet therapy. Methods : Subjects were consecutive 110 STEMI patients presented within 6hrs of pain onset from march 2003 to June 2006. 55 patients underwent primary PCI and another 55 patients underwent routine deferred PCI within 48 to 76hrs after thrombolytic therapy. In-hospital, 30 days, 12 months clinical outcomes of primary PCI and early deferred PCI were assessed. Results : The baseline clinical characteristics were similar between 2 groups. In-hospital events such as death(P=0.50), Re-MI(P=0.50) or revascularization(P=0.059) showed no statistical difference between the two groups. 30 days, 12 months results are shown in table. Conclusion : In reperfused STEMI patients with fibrinolytics, early post-thrombolysis deferred PCI is needed because incidence of clinical events such as death, Re-MI or revascularization was similar compared to primary PCI.