| ǥ :
|
ȣ - 500572 63 |
| Feasibility of Segmental Topographic Assessment with Computed Tomographic Angiography for Evaluation of Coronary Vasodilation Function
|
| 관동대학교 의과대학 명지병원 심장 센터, 심장 내과¹ , 심장 소아과² |
| 변기현¹, 은영민², 민필기¹, 조덕규¹, 박일운¹, 조지훈¹ |
Background : Vasodilatory disturbance is considered due to endothelial dysfunction. Non-invasive assessment of coronary vasodilation has been limited. The aim of this study was to investigate usfulness of multi-detector computed tomography (MDCT) for vasodilation function.
Method : Baseline coronary CT was performed in 5 volunteers using 16 channel MDCT with 3 days beta blocker, then reperformed with nitroglycerin in 2 days. Cross sectional luminal diameters and areas of 122 segments in 15 coronary arteries were measured by the dedicated software. Each segment assigned to proximal, mid, and distal group, and the measures were compared.
Results : Nitroglycerin resulted in increased coronary diameter and area at mid and distal portions(p<0.05).
Conclusion : Segmental Topographic Assessment with MDCT may be useful for non-invasive measurement of coronary vasodilation.
|
|
Coronary artery measures |
pre |
post |
p-value |
|
RCA |
proximal |
diameter |
3.47
± 0.56 |
3.63
± 0.62 |
ns |
|
area |
9.69
± 3.12 |
10.73
± 3.12 |
ns |
|
mid |
diameter |
3.01
± 0.60 |
3.30
± 0.53 |
0.03 |
|
area |
7.37
± 3.02 |
8.80
± 2.76 |
0.05 |
|
distal |
diameter |
2.70
± 0.52 |
3.16
± 0.54 |
0.0001 |
|
area |
6.00
± 2.30 |
8.00
± 2.66 |
0.0004 |
|
LAD |
proximal |
diameter |
3.56
± 0.84 |
3.69
± 0.50 |
ns |
|
area |
10.45
± 5.03 |
10.84
± 3.01 |
ns |
|
mid |
diameter |
2.63
± 0.47 |
3.17
± 0.50 |
0.0006 |
|
area |
5.65
± 1.99 |
8.06
± 2.47 |
0.0006 |
|
Distal |
diameter |
2.22
± 0.34 |
2.62
± 0.37 |
0.007 |
|
area |
3.94
± 1.25 |
5.45
± 1.47 |
0.008 |
|
LCX |
proximal |
diameter |
2.91
± 0.54 |
3.15
± 0.69 |
0.01 |
|
area |
6.90
± 2.37 |
8.14
± 3.59 |
0.02 |
|
distal |
diameter |
2.20
± 0.42 |
2.61
± 0.51 |
0.0002 |
|
area |
3.93
± 1.40 |
5.52
± 2.25 |
0.0005 |
?
|
|
|
