Background: The causes of sudden cardiac death (SCD) are variable. However, the ventricular fibrillation (VF) caused by electrical unstability is the main final cause of SCD. Magnetocardiography (MCD) is a new noninvasive tool to evaluate the depolarizaiton and repolarization abnormality of heart. The objective of this study was to evaluate the MCG findings of SCD survivals with a 64-channel MCG and to confirm in MCG simulation model.
Methods: The MCG findings of 9 SCD survivals (all male, 37.0 짹 7.7 years) and 8 control (6 male, 40.4 짹 17.1 years) were analyzed. All SCD survivals had experienced VF, and the underlying disease was as follows ; 4: Brugada syndrome, 2: coronary artery disease, 2 idiopathic, 1: hypertrophic cardiomyopathy. Magnetic field (MF) and conduction density vector (CDV) map were evaluated every 10 msec from the onset of QRS and the end of T-wave (Te). Especially during repolarization, MF map was classified into dipole and non-dipole, In CDV map during repolarization, the number of vortexes was calculated.
Results: MCG was recorded 6.2 짹 8.8 days after VF. SCD survival had more non-dipole pattern in MF map and more vortexes in CDV map than normal from Te-20 ms and Te-60 ms. This dispersion of repolarization was changed with variable ECG changes in Brugada syndrome patients. In MCG simulation model, Brugada syndrome and myocardial ischemia showed magnetic dispersion of repolarization.
Conclusion: In all SCD survival, the dispersion of repolarization was observed. This magnetic dispersion pattern can be the common finding in SCD survival and MCG might be used as a new noninvasive tool to evaluate SCD survival.