BACKGROUND: Long-length stenting has a poor outcome when bare metal stents are used. The safety and efficacy of the DES in long lesions has not been evaluated. Therefore, the aim of the present study was to evaluate the clinical and angiographic outcomes and the factors associated with the occurrence of restenosis of DES implantation over long coronary artery segment. METHODS : The present study population was composed of 70 patients (77 lesions) for whom angiographic 6 month follow-up data were obtained and incidence of major cardiac adverse events (death, nonfatal myocardial infarction, and target lesion revascularization) and significant clinical, angiographic, and procedural predictors of post-SES restenosis were evaluated. Results : Demographics are as follows ; median age was 64 years ; 67% was male ; median follow-up duration was 191 days. Mean stented length per lesion was 58.6 +/- 16.2 mm .Target lesion revascularization was needed in 10 % of lesions . There were 1 deaths (0.2%) and major adverse cardiac event (MACE) was 10.4% .The following characteistics were identified as multivariate predictors of TLR and MACE : diabetes for (0.21 for TLR, P=0.06), MLD at follow-up ( - 0.63 for TLR, p=0.001 ; -0.586 for MACE , p=0.001) , angulation (- 0.231 for TLR , p<0.05) , tortuosity ( - 0.244 for TLR , p<0.05) CONCLUSIONS: Angiographic restenosis after DES implantation in long lesion is an infrequent event and DES implantation appears safe and effective. We showed that restenosis is mainly in association with lesion-based characteristics and diabetes mellitus.