학술대회 발표 연제 초록

Background: In patients with hypertrophic cardiomyopathy (HCM), delayed hyperenhancement (DE) in MRI is considered to be in concordance with the myocardial fibrosis. The aim of this study was to determine whether the extent of DE is associated with the functional status and left ventricular (LV) function in patients with HCM. Method: We studied 40 patients with HCM (27 male, mean age 53 짹 13, 10 with LV outflow tract obstruction) who had undergone MRI and echocardiography within 3 month interval. Results: DE was present in 32 (80%) of 40 patients and its mean mass was 41.4 짹 41.6 gm and mean percentage to LV mass was 18.9 짹 18.2%. The associations between extent of DE and clinical and echocardiographic parameters are summarized in Table 1. In the third tertile, maximal thickness, peak systolic annulus velocity and left atrial volume index (LAVI) were significantly different from those of the first tertile. Conclusions: The extent of myocardial scarring seems to be associated with maximal thickness, decreased regional wall performance and chronic LV diastolic burden rather than with resting functional status and resting diastolic dysfunction in patients with HCM.