Purpose: Doppler myocardial imaging (DMI) has been suggested as a method of quantifying induced ischemia during dobutamine stress echocardiography (DSE). Post-systolic motion (PSM) detected by DMI is related with peri-infarct ischemia at DSE. We hypothesized that PSM during DSE would predict functional recovery of dysfunctional myocardium after successful percutaneous coronary intervention (PCI). Methods: Among 30 patients with dysfunctional myocardium on left anterior descending coronary artery (LAD) territory, we divided into two groups according to the improvement of wall motion score index (WMSI) on LAD territory at 6 months after successful PCI on LAD, and evaluated DMI on the LAD territory during DSE in both 15 improved WMSI (1.42짹0.39) patients and 15 no changed WMSI (1.75짹0.46) patients at 1 month after PCI. Myocardial velocity data were measured in the mid-septal, apico-septal, and basal anterior segment of LAD territory. PSM was defined as positive wave, which appeared after the curve of systolic ejection had reached the zero line. Results: There was no difference of resting PSM in both groups. However, PSM during DSE was significantly higher in improved WMSI group than in no changed group. Conclusions: We suggest that PSM during DSE would predict functional recovery of dysfunctional myocardium after successful PCI on LAD.