| ǥ :
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ȣ - 490314 38 |
| Long-Term Results of Sirolimus-Eluting Stents Compared to Bare Metal Stents for patients with Acute Myocardial Infarction |
| Division of Cardiology, Dongsan Medical Center, Keimyung University, Daegu, Korea |
| Young-Soo Lee, Kee-Sik Kim, Chang-Wook Nam, Seong-Wook Han, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim |
Purpose:Sirolimus-eluting stent (SES) have recently been proven to reduce restenosis and reintervention compared with bare metal stents (BMS). Effectiveness of SES in acute myocardial infarction (AMI) remains unknown. The aim of this study was to evaluate the efficacy of a SES implantation in patients with AMI compared to BMS Methods: From January 2003 to June 2004, angioplasty was performed with SESs in 108 patients (123 lesions) with AMI who were compared with 108 patients (130 lesions) treated with BMSs. The incidence of major adverse cardiac events (MACE : angina, heart failure, death, nonfatal MI, and target lesion revascularization (TLR)) and binary angiographic restenosis were evaluated at 1 year. Results: The results are as follows; Conclusion: The SES implantation may be safe and effective strategy for the treatment in patients with AMI in terms of early and late clinical outcomes.
|
|
|
BMS |
DES |
p
|
|
Baseline
characteristics |
N=108 |
N=108 |
|
|
Age (yr) / Male
(%) |
61 ± 10 / 78
(72.2%) |
62 ± 11 / 79
(73.1%) |
NS |
|
Hypertension
(%) |
36
(33.3%) |
49
(45.4%) |
<0.05 |
|
In
hospital outcomes |
|
|
|
|
Stent thrombosis / Death
(%) |
1(0.9%) /
0 |
1(0.9%) /
0 |
NS |
|
Nonfatal MI
(%) |
8
(12.3%) |
7
(7.4%) |
NS |
|
MACE @ 1yr |
26
(24.1%) |
5
(4.6%) |
<
0.01 |
|
Death / Stroke
|
2 (1.9%) /
4(3.7%) |
0 / 2(1.9%)
|
NS |
|
TLR |
15
(23.1%) |
2
(4.3%) |
0.005 |
|
Lesion
characteristics |
N=123 |
N=130 |
|
|
Pre MLD |
0.40 ±
0.34 |
0.35 ±
0.27 |
NS |
|
Acute gain |
2.96 ±
0.48 |
2.66 ±
0.84 |
<
0.001 |
|
CAG FU @ 6
Mo |
78
(63.4%) |
75
(57.7%) |
|
|
Late loss |
1.38 ±
0.97 |
0.48
±1.21 |
<
0.001 |
|
ISR |
28
(35.9%) |
5
(6.7%) |
<
0.001 |
|
|
|
