Background: Drug eluting stents(DES) had been reported to have favorable results in various clinical settings. However, their role in diabetic patients has not been evaluated fully. Therefore we tried to evaluate the effects of 2 different DES on diabetic patients. Methods: From April 2003 to January 2005, 190 lesions in 169 patients (mean age 62짹8, male: 112) were randomly assigned to use DES in a 5 different centers. Two coronary arteries were allowed to enroll in a single patient. Exclusion criteria were as follows: serum creatinine>3.0 mg/dL, reference vessel size<2.0 mm, diffuse lesion requiring more than 3 DES. Results: Treated arteries were LAD in 92(48%), LCx in 34(18%) and RCA in 64 lesions(34%). Risk factors were hypertension in 111(66%), hypercholesterolemia in 52(33%) and current smoker in 46(28%). Multivessel interventions were done in 29(17%) and multiple overlapping stents were inserted in 16(8%). Clinical data are listed in the table. Six-month angiographic follow-up was done in 105(55.3%) of the patients so far. Restenosis occurred in 3(5.8%) of cypher and 4(7.5%) of taxus arm. Conclusion: Both DES showed low 6-month restenosis rate so far. Final results will be presented.