| ǥ :
|
ȣ - 480488 213 |
| Echocardiographic Characteristics in Patients with Myocardial Hypertrophy |
| Division of Cardiology, Internal Medicine, Dongsan Medical Center, Keimyung University |
| Sang-Hoon Lee, Kee-Sik Kim, Chang-Wook Nam, Young-Soo Lee, Mi-Sook Kang, Soo-Yeon Kim, Seong-Wook Han, Seung-Ho Hur, Yoon-Nyn Kim, Kwan-Bae Kim |
Background: Transthoracic echocardiography provides noninvasive measurement of coronary flow velocity in the distal epicardial coronary arteries. The aims of this study were to characterize regional left ventricular systolic and diastolic function by myocardial doppler imaging and to evaluate the relation of coronary flow velocity and other conventional echocardiographic parameters in patient with septal, apical and concentric hypertrophy. Method: In 47 patients (12 septal hypertrophy, 9 apical hypertrophy, 11 concentric hypertrophy, 15 normal), we measured basic echocardiographic parameter, peak velocity, time-velocity integral, and deceleration time of left anterior descending artery blood flow and the systolic strain at apical 4 chamber view. Results: See the below table. Conclusion: Hypertrophied myocardium had abnormality of myocardial deformation related to the degree of hypertrophy. Myocardial doppler imaging offered an approach to quantify regional systolic and diastolic dysfunction.
|
|
|
|
S-HCM |
A-HCM |
LVH |
Normal |
|
IVSd (cm) |
1.66±0.27 |
1.13±0.24 |
1.42±0.25 |
0.83±0.12 |
|
LVPWd (cm) |
0.81±0.87* |
0.92±0.13 |
1.15±0.35*,† |
0.92±0.23† |
|
IVRT (msec) |
117.9±19.2* |
119.6±23.8† |
117.6±11.2# |
94.8±18.3*, †,
# |
|
LV mass index
(g/m2) |
100.2±27.6* |
92.7±20.3† |
91.5±34.0# |
49.3±20.6*, †,
# |
|
Coronary blood flow |
|
|
|
|
|
Diastolic velocity
(cm/s) |
0.37±0.14* |
0.31±0.08 |
0.27±0.12 |
0.21±0.08* |
|
Systolic TVI
(cm) |
2.78±1.30 |
2.80±1.25 |
3.67±0.98* |
2.03±0.92* |
|
Systolic strain (%) |
|
|
|
|
|
Basal
septum |
-14.5±6.5* |
-17.5±8.4 |
-11.6±8.4† |
-26.9±9.8*,† |
|
Mid
septum |
-9.1±9.9* |
-13.4±9.7 |
-14.9±10.1† |
-26.3±9.2*,† |
|
Apical
septum |
-19.3±13.0* |
-4.8±3.0*, †,
# |
-20.3±4.8† |
-20.6±7.0# |
|
Mid lateral
wall |
-14.2±5.7 |
-8.4±3.8* |
-11.7±6.4 |
-20.1±8.6* |
|
Apicolateral
wall |
-11.2±4.0 |
-5.1±5.9* |
-17.6±10.6* |
-11.9±5.7 |
*, †, #; p<0.05 in each
compared group.
|
|
|
