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ȣ - 480473 241 |
| The epicardial coronary artery morphology and coronary flow dysfunction with Slow coronary flow
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| Department of Cardiology, College of Medicine, Kwandong University, Goyang, Korea. |
| Jong-Hoon koh, Geun-Jun Koh, Hyung-Seob Choi, Sang Soo Kim, Gi-Hyun Byun. |
Objective: Slow coronary flow(SCF) is characterized by delayed opacification of coronary arteries without epicardial focal stenosis at angiography. We assessed functional stenosis and morphology of epicardial coronary artery with SCF by using fraction flow reserve (FFR) and Intravascular ultrasound (IVUS).
Methods: We obtained from 12 arteries in 10 patients with SCF and 10 arteries in 10 patients without SCF. Aortic pressure(Pa) and pressure(Pd), flow velocity(v) were measured and obtained during maximal hyperemia. FFR(Pd/Pa) with Pressure-Wire and Maximal Intima + Media thickness(IMA) were calculated by IVUS.
Results: With SCF, IMA increased (0.35±0.5 vs 0.12±0.7mm, p<0.05), FFR was significantly lower (0.89±0.05 vs 0.95±0.03, p< 0.05) and h-MVRI values was significant higher (2.26±0.39 mmHg vs 2.86±0.8 mmHg/cm/s, p<0.05) compared with without SCF.
Conclusion: This study suggested that SCF may be a sign of early diffuse atherosclerosis invloving coronary flow functional impairment even if the absence of epicardial occlusion disease at angiograhy
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