Purpose: Doppler myocardial imaging (DMI) has been suggested as a method of quantifying induced ischemia during dobutamine stress echocardiography (DSE). Post-systolic motion (PSM) detected by DMI is related with peri-infarct ischemia at DSE. The aim of this study is to evaluate the efficacy of PSM to detect residual ischemia after PCI. We compared DMI of the infarct and non-infarct related coronary artery after successful PCI. Methods: DMI was recorded at each stage of a DSE in 15 anterior myocardial infarction patients (15 male, 57.6짹12.9 years) and 20 chronic stable angina (10 male, 61.3짹8.6 years) at 4 weeks after successful PCI at left anterior descending coronary artery (LAD). Myocardial velocity data were measured in the mid-septal, apical septal, and basal anterior segment of LAD territory. PSM was defined as positive wave, which appeared after the curve of systolic ejection had reached the zero line. Results: The PSM velocity at rest and stress, ratio PSM and S velocity at stress and change of PSM velocity in infarct segment were significantly faster than those in non-infarct segment. Conclusions: The PSM detected by DMI during DSE may predict residual ischemia after successful PCI.