학술대회안내사전등록초록등록안내초록등록/관리숙박 및 교통
초록심사

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ǥ : ȣ - 480425   267 
Myocardial bridging: prevalence, morphology, clinical presentation and coronary angiographical characteristics
서울대학교의과대학 내과학교실; 서울대학교병원 임상의학연구소 심혈관연구실; 서울대학교병원 심혈관센터
정중화, 박진식, 조현재, 강현재, 구본권, 김효수, 손대원, 오병희, 이명묵, 박영배, 최윤식
Background: Myocardial bridging is the most common inborn coronary anomaly. Though in most cases this is considered as a harmless vessel malformation, it causes myocardial ischemia in some patients. This study was performed to evaluate clinical and angiographical characteristics and clinical outcomes of the Korean patients with myocardial bridging. Methods and Results: We studied 123 patients (1.87%) with myocardial bridging out of 6583 consecutive patients underwent coronary angiography from January 1999 to July 2003. The mean age was 58 ± 10 years and male was 74%. Myocardial bridging was the only angiographic abnormality in 32 patients. Myocardial perfusion scan was performed in 32 patients and 8 (25%) of them showed a reversible perfusion defect at the territories of bridging segments. The mean length of bridging segments and % stenosis during systole were 21 ± 11 mm and 60 ± 15%, respectively. Myocardial bridging is most commonly localized in the middle segment of the left anterior descending coronary artery (97 patients, 71%). Thirty-three patients (27%) had left ventricular hypertrophy in echocardiogram. We modified bridging types by Ferreira to 3 types: perpendicular (superficial, 81%), transverse (deep, 14%), and mixed (5%). There was a significant correlation between symptom severity and the type of bridging in stable angina patients (correlation coefficient = 0.34, p=0.03). Patients were divided into the 2 groups according to the presence of stenosis at just proximal to bridging segments. (Stenosis group: 42 patients (34%)). There were no significant differences in clinical and angiographical characteristics of bridging segments between the 2 groups except more frequent smoker in stenotic group (p-0.04). During follow-up (mean 21 ± 14 months) of 32 patients with normal coronary artery except myocardial bridging, no major cardiac events occurred. Conclusions: There was a higher incidence of proximal stenosis and LV hypertrophy in patients with myocardial bridging. Deeper and more complex myocardial bridging were associated with symptom severity.


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