학술대회안내사전등록초록등록안내초록등록/관리숙박 및 교통
초록심사

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Is there also benefit of percutaneous coronary intervention(PCI) with drug-eluting stent(DES) at diffuse coronary artery lesion?
가천의대 길병원 심장혈관센터 심장내과¹ , 고려대학교 의과대학 안암병원 심장내과²
강웅철¹, 안태훈¹ , 신성희² , 한승환¹ , 오규진¹ , 최경림¹ , 심완주² , 임도선² , 최인석¹ , 신익균¹ , 노영무²
Background : The treatment of diffuse coronary artery lesions in one of the most challenging problems for interventional cardiologist. Although coronary stenting has improved the procedure success rate, high restenosis rate is remaining problem. The objective of this study is to compare the efficacy of DES and bare metal stent(BMS) in treating diffuse (>30mm) coronary lesions. Method : We analyzed 104 patients with diffuse coronary artery lesion who implanted DES(n=60, 43 males, mean ages 59.6±9.6 years) or BMS(n=44, 31 males, mean ages 60.2±10.9 years). Clinical follow-up was performed at one month and six months and, in case of DES, we performed follow-up angiography at nine months. Results : Baseline clnical and angiographic characteristics in both group were similar. Angiographic success rate were 100% in both groups. A follow-up angiography was performed in 30 patients(28.8%) including 14 patients in BMS group. Most follow-up angiography will be performed within next two months. Although there was no significant statistical difference, the rate of restenosis trend to lower in DES group(4/16, 25.0%) than in BMS group(8/14, 57.1%)(p=0.073). And interestingly, type of restenosis was different between both groups. In DES group, incidence of edge restenosis was higher than in BMS group(3/4, 75.0% vs 1/8, 12.5%, p=0.030), No patient who showed acute or subacute thrombotic stent occlusion was observed at both group. The incidence of MACE at one month (1/59, 1.7% vs 1/44, 2.3%, p=0.824) and at six month(3/60, 5.0% vs 4/40, 10.0%, p=0.411) was not different between both groups. Conclusion : Although, in diffuse coronary lesion, PCI with DES showed trending to lower restenosis rate, the incidence of MACE was not different between both groups during follow-up period.


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