학술대회안내사전등록초록등록안내초록등록/관리숙박 및 교통
초록심사

мȸ ǥ ʷ

ǥ : ȣ - 480210   200 
The Usefulness of Color M-mode Doppler Echocardiographic Indices in the Assessment of Left Ventricular Diastolic Function
Department of Cardiovascular Medicine, Chonnam National University Hospital¹, Department of Cardiovascular Medicine, Wonkwang University Hospital²
Kyung Ho Yun¹, Jong Chun Park¹, Dong Goo Kang¹, Kye Hun Kim¹, Seo Na Hong¹, Sang Yup Lim¹, Yeon Sang Lee¹, Sang Hyun Lee¹, Young Joon Hong¹, Ju Han Kim¹, Young Keun Ahn¹, Myung Ho Jeong¹, Jeong Gwan Cho¹, Seok Kyu Oh², Nam-Ho Kim², Jin-Won Jeong² and Jung
Background and Objectives : Early color M-mode Doppler flow propagation (Vp) has been used to distinguish pseudonormal from normal diastolic filling patterns. But the role of other indices including late diastolic propagation velocity (Ap), time delay of mitral flow propagation (VpTD and ApTD) is not clear. Subjects and Methods : Doppler echocardiographic examination was performed in 89 patients (60.6±9.9 years, male 59.6%) with ejection fraction ≥40% who were admitted for diagnostic coronary angiography. The clinical diagnoses on admission were stable angina (41.6%), unstable angina (30.3%), old myocardial infarction (24.7%) and atypical chest pain (3.3%). The diastolic filling patterns confirmed by mitral inflow and pulmonary venous flow were compared with the indices of Ap, VpTD and ApTD by color M-mode Doppler echocardiography. Results : Age, left ventricular ejection fraction, left ventricular end diastolic and end systolic dimension, left atrial size, E' and A' velocity of mitral annulus tissue Doppler were different significantly between patients with normal and abnormal diastolic filling patterns. In patients with normal filling, impaired relaxation and pseudonormalized filling pattern, VpTD were 63.1±14.9 ms, 85.2±25.5 ms and 107.8±36.8 ms (p<0.001), E/Vp 1.3±0.4, 1.6±0.6 and 3.1±0.7 (p<0.001), and E/VpTD 1.2±0.5, 0.7±0.2 and 0.9±0.4 (p<0.001), respectively. Ap and ApTD showed significant difference between patients with normal filling pattern and those with pseudonormalized filling pattern (Ap 58.3±23.5 vs. 36.2±15.1, p=0.000; ApTD 47.1±19.5 vs. 66.7±22.2, p=0.001). PVa duration, the index depending on left ventricular end-diastolic pressure, was the most important independent predictor for ApTD by multiple regression analysis (R2=71.4%). Conclusion : The color M-mode Doppler indices of Ap, VpTD and ApTD are new diagnostic parameters for diastolic dysfunction.


[ư]